One-StepGem-Diphosphorylation of Amides and Lactams
نویسندگان
چکیده
منابع مشابه
Reliable determination of amidicity in acyclic amides and lactams.
Two independent computational methods have been used for determination of amide resonance stabilization and amidicities relative to N,N-dimethylacetamide for a wide range of acyclic and cyclic amides. The first method utilizes carbonyl substitution nitrogen atom replacement (COSNAR). The second, new approach involves determination of the difference in amide resonance between N,N-dimethylacetami...
متن کاملSynthesis of amides and lactams in supercritical carbon dioxide.
Supercritical carbon dioxide can be employed as an environmentally friendly alternative to conventional organic solvents for the synthesis of a variety of carboxylic amides. The addition of amines to ketenes generated in situ via the retro-ene reaction of alkynyl ethers provides amides in good yield, in many cases with ethylene or isobutylene as the only byproducts of the reaction. Reactions wi...
متن کاملPreparation of - and -lactams from carbamoyl radicals derived from oxime oxalate amides†
hydrogen from the solvent. The resulting peroxyl radicals, (14f,g) couple in pairs, extrude dioxygen, and generate alkoxyl radicals 15f,g that are very good H-atom abstractors and hence afford the hydroxylated products. Analogous hydroxylation sequences are well known. Iminyl radicals (PhC(H) N ) were produced as co-intermediates with the aminoacyls 10. The major product derived from this speci...
متن کاملFast Solvent-free Alkylation of Amides and Lactams under Microwave Irradiation
N-Substituted amides and lactams are rapidly N-alkylated under solvent-free phase-transfer catalytic conditions using microwaves.
متن کاملMulticomponent ternary cocrystals of the sulfonamide group with pyridine-amides and lactams.
SMBA was selected as a bifunctional sulfa drug to design ternary cocrystals with pyridine amides and lactam coformers. Supramolecular assembly of five ternary cocrystals of p-sulfonamide benzoic acid with nicotinamide and 2-pyridone is demonstrated and reproducible heterosynthons are identified for crystal engineering.
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ژورنال
عنوان ژورنال: Synthetic Communications
سال: 2000
ISSN: 0039-7911,1532-2432
DOI: 10.1080/00397910008087363